Bendiocarbamate effect on the central nervous system in the chick embryo

Abstract

The aim of the study was to investigate toxicity of bendiocarbamate (2,3-isopropyledene-dioxyphenyl methylcarbamate) to the central nervous system of the chick embryo. Bendiocarbamate was administered to chick embryos on day 3 (500 µg.egg-1) and on day 10 (800 µg.egg-1) of the incubation. The observations showed no microscopic changes in the central nervous system with the dose and day of incubation when bendiocarbamate was administered. The central nervous system was also investigated for caspase activity in relation to application of bendiocarbamate, and no differences in the number of cells with the caspase immunoreactivity were observed compared to the control.