• Rudolf DUPAK Slovak University of Agriculture in Nitra, Department of Animal Physiology, Faculty of Biotechnology and Food Sciences, Nitra, Slovak Republic
  • Marcela CAPCAROVA Slovak University of Agriculture in Nitra, Department of Animal Physiology, Faculty of Biotechnology and Food Sciences, Nitra, Slovak Republic


diabetes, human, animal model, diet


Animal models are widely used to imitate human diseases to improve the understanding of the pathophysiology of disease and to test treatment interventions. A chronic disease, such as diabetes mellitus, is a fast-growing epidemy worldwide connected with obesity, lack of physical exercise, aging and genetics. This review brings an introduction to diabetes mellitus and compares individual animal models, mainly rodents, with respect to this disease. The selection of a suitable model is important and essential for the progression of new therapeutic methods of preclinical and clinical studies.


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